stem cell therapy
This treatment aims to prevent the progression of arteriosclerosis by intravenously administering adipose-derived mesenchymal stem cells, which are harvested and cultured from the patient's own fat .
Tokyo Private Clinic
Officially from the Ministry of Health, Labour and Welfare
"Type 2 Regenerative Medicine Provision Plan Number PB3190066"
This is a medical institution that has obtained the necessary certification.
"Using autologous adipose-derived mesenchymal stem cells"
Treatment for arteriosclerosis
Type 2, Project Number PB3190066
What are stem cells?
① Self-renewal ability: The ability to divide into stem cells that possess the same capabilities as itself.
② Differentiation ability... the ability to create various cells that make up the body.
Cells that possess both of these characteristics are called stem cells.
These are important cells involved in the repair and regeneration of the body.
The human body has a mechanism to repair damaged or weakened parts.
Regenerative medicine using stem cells is a type of medical treatment that aims to restore the body to its normal function by amplifying the repair function of stem cells tens or even millions of times, and intensively acting on damaged blood vessels and dysfunctional organs to restore their function.
In short, stem cell therapy uses the power of your own "cells" to restore bodily functions that you couldn't achieve on your own through exercise, diet, or rest.
Stem cells decrease rapidly with age.
However, its regenerative capacity is not zero.
The fundamental principle of stem cell therapy is to maximize the remaining power of stem cells and amplify their regenerative capabilities.
arteriosclerosis
Arteriosclerosis is a disease in which excessive bad cholesterol, caused by stress, lack of exercise, smoking, excessive salt intake, and aging, causes the arteries, which are the pathways for blood vessels, to lose their elasticity, become hard and brittle, and narrow.
Arteriosclerosis is a very frightening disease that increases the risk of developing obesity, hypertension, diabetes, and in the worst cases, can lead to stroke, myocardial infarction, and nephropathy, potentially resulting in a state of needing long-term care, dementia, dialysis, and even necrosis of the feet.
Stem cells have the ability to replicate themselves and differentiate into various cell types, which helps improve blood flow and regenerate blood vessels.
Furthermore, adipose-derived stem cells have the property of secreting substances that have an anti-inflammatory effect, and by suppressing inflammation, they are expected to prevent the worsening of symptoms.
However, the same or expected effects may not occur for all patients.
Please be sure to consult thoroughly with your doctor before starting treatment.
Furthermore, the most important thing to prevent myocardial infarction and stroke caused by arteriosclerosis from becoming critical is to prevent arteriosclerosis from progressing.
The goal of treatment is to slow the progression of arteriosclerosis and prevent the onset of life-threatening diseases.
This is recommended for people like this.
Individuals who meet any of the following selection criteria and are judged to have arteriosclerotic lesions.
CAVI value (Cardio-Ankle Vascular Index) ≥ 8.0
ABI (Ankle-Brachial Index) ≤ 0.9
Carotid artery ultrasound examination reveals plaque (IMT ≥ 1.1) in the carotid arteries (common carotid artery, internal carotid artery).
This is also recommended for those who meet the following criteria.
History of myocardial infarction or angina pectoris
Coronary CT scans reveal irregularities, calcification, stenosis, and occlusion of the coronary artery wall.
History of cerebral infarction
A stroke was detected in the head via MRI and MRA.
Two or more blood relatives within the second degree of kinship have arteriosclerotic disease.
Genetic testing indicated a high predisposition to arteriosclerosis.
If you have any of the following conditions and existing treatments (conservative treatment, surgical treatment) are insufficient,
We also recommend this to those whose symptoms have not improved sufficiently.
cerebral infarction
myocardial infarction
arteriosclerosis obliterans
Buerger's disease
Expected effects
Stem cells that enter the body are expected to participate in the repair of damaged tissue and promote tissue regeneration.
It is believed that cytokines secreted by stem cells have an anti-inflammatory effect, and at the same time , they produce substances that promote blood vessel regeneration and substances that promote blood vessel regeneration in tissues suffering from insufficient blood flow, thus promoting the restoration of blood flow.
Blood purification therapy
Blood purification therapy directly removes disease-causing factors such as bad cholesterol, triglycerides, inflammatory substances, and viruses from the blood.
Furthermore, removing these substances helps prevent blood clots and plaque buildup, preventing thick blood from sticking to or blocking blood vessels.
The reason Tokyo Private Clinic can perform blood purification therapy and stem cell therapy simultaneously is because it is a specialized clinic that focuses more specifically on blood vessels.
Treatment process
1. Fat harvesting (approximately 10 minutes)
Fat is harvested from the abdomen. Local anesthesia is used, so there is no significant pain.
A small incision of about 5 mm is made along the wrinkles, and a small amount of fat, about the size of 2-3 grains of rice, is harvested.
The scar is in a barely noticeable location and the incision is small enough that stitches are not necessary, but in some cases, dissolvable sutures may be used.
*No stitches need to be removed.
2. Blood sample collection (approximately 10 minutes)
Approximately 100-140cc of blood is drawn to be used for cell culture.
A portion of the sample will be sent for testing to check the overall condition.
It's not enough to cause anemia, but please make sure to drink plenty of fluids on that day.
*Please refrain from drinking alcohol and take only a shower instead of a bath.
3. Cultivation (approximately 3-4 weeks)
After fat is harvested, our clinic collaborates with a specialized cell culture laboratory that possesses the highest level of technology in Japan, and immediately transports the fat under strict temperature control.
Upon arrival at the facility, dedicated culture specialists cultivate the adipose-derived stem cells in a sterile cell culture processing room for approximately 3 to 4 weeks.
We maintain close cooperation, including having a system in place to receive regular reports on the culture status.
We will prepare everything so that it is served in the best possible condition at your reserved time.
The medication is administered intravenously through a vein in the arm. There is usually no pain whatsoever.
*Please refrain from drinking alcohol on the day of administration.
4. Administration (Duration: 1-1.5 hours)
Features of our clinic
Tokyo Private Clinic is one of the few clinics in Japan that offers stem cell therapy for arteriosclerosis.
Because treatment is provided by vascular surgeons with extensive clinical experience, more specialized treatment can be performed.
We cultivate only highly active cells in a cell culture processing facility that meets strict hygiene standards, under the supervision of dedicated cell culture specialists, and then provide them to our customers.
If the number of cells is too high, the cell density increases and the quality deteriorates. Therefore, by calculating the optimal number of cells based on the treatment content and the patient's physique, a more effective treatment can be expected.